Abstract:The article analyzes the problems of insufficient medical process coordination, unreasonable load estimation, cross disciplinary interference, and lack of maintenance in the current hospital water supply and drainage engineering, and proposes an optimization system covering the entire stages of planning, design, construction, and operation. The results of engineering examples show that full process collaborative optimization can effectively improve the system's operational safety, water supply and drainage guarantee capability, and operation and maintenance management level, providing technical reference for the high-quality construction of modern comprehensive hospital water supply and drainage systems.